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Browsing Urine Metabolite Diseases and Conditions
Clicking on any metabolite link will take you to the Human Metabolome Database.
2-Ketoglutarate dehydrogenase complex deficiency (203740 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Oxoglutaric acid (HMDB0000208) | 101.0 (50.0-152.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both |
| details |
| Oxoglutaric acid (HMDB0000208) | 875.0 (150.0-1600.0) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both |
| details |
| Fumaric acid (HMDB0000134) | 17-124 umol/mmol creatinine | Abnormal | Infant (0-1 year old) | Male | details | |
| L-Malic acid (HMDB0000156) | 7-194 umol/mmol creatinine | Abnormal | Infant (0-1 year old) | Male | details | |
| Oxoglutaric acid (HMDB0000208) | 30-1600 umol/mmol creatinine | Abnormal | Infant (0-1 year old) | Male | details | |
| Succinic acid (HMDB0000254) | 75-185 umol/mmol creatinine | Abnormal | Infant (0-1 year old) | Male | details |
3-Hydroxy-3-methylglutaryl-CoA lyase deficiency (246450 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| 3-Hydroxyisovaleric acid (HMDB0000754) | 2030.0 (60.0-4000.0) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both |
| details |
| 3-Methylcrotonylglycine (HMDB0000459) | 225.0 (0.00-450.0) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both |
| details |
| 3-Methylglutaconic acid (HMDB0000522) | 5070.0 (140.0-10000.0) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both |
| details |
| Methylglutaric acid (HMDB0000752) | 507.0 (14.0-1000.0) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both |
| details |
| Adipic acid (HMDB0000448) | 31.0 (12.0-50.0) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both |
| details |
| 3-Hydroxymethylglutaric acid (HMDB0000355) | 481 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Female | details | |
| 3-Methylglutaconic acid (HMDB0000522) | 3714 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Female | details | |
| Methylglutaric acid (HMDB0000752) | 622 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Female | details | |
| 3-Hydroxyisovaleric acid (HMDB0000754) | 851 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Female | details | |
| 3-Hydroxymethylglutaric acid (HMDB0000355) | 1028.4 umol/mmol creatinine | Abnormal | Newborn (0-30 days old) | Male | details | |
| 3-Methylcrotonylglycine (HMDB0000459) | 27.6 umol/mmol creatinine | Abnormal | Newborn (0-30 days old) | Male | details | |
| 3-Methylglutaconic acid (HMDB0000522) | 4166.4 umol/mmol creatinine | Abnormal | Newborn (0-30 days old) | Male | details | |
| Glutaric acid (HMDB0000661) | 1274.9 umol/mmol creatinine | Abnormal | Newborn (0-30 days old) | Male | details | |
| Methylglutaric acid (HMDB0000752) | 348 umol/mmol creatinine | Abnormal | Newborn (0-30 days old) | Male | details | |
| 3-Hydroxyisovaleric acid (HMDB0000754) | 1154.8 umol/mmol creatinine | Abnormal | Newborn (0-30 days old) | Male | details |
Succinic semialdehyde dehydrogenase deficiency (271980 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| (S)-3,4-Dihydroxybutyric acid (HMDB0000337) | 810-1160 umol/mmol creatinine | Abnormal | Infant (0-1 year old) | Male | details | |
| 4-Hydroxybutyric acid (HMDB0000710) | 880-3630 umol/mmol creatinine | Abnormal | Infant (0-1 year old) | Male | details |
Acrodermatitis enteropathica (201100 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Zinc (HMDB0015532) | 11.619 umol/mmol creatinine | Abnormal | Children (1-13 years old) | Male | details |
Appendicitis
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Indoleacetic acid (HMDB0000197) | 3.5 +/- 0.33 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Indoleacetic acid (HMDB0000197) | 3.1 +/- 0.14 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details |
Acute intermittent porphyria (176000 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Porphobilinogen (HMDB0000245) | 57.1 (19.6-132.7) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 5-Aminolevulinic acid (HMDB0001149) | 11.0 (95.8-28.7) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Porphobilinogen (HMDB0000245) | 17.2 (74.9-41.6) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 5-Aminolevulinic acid (HMDB0001149) | 6.6 (34.8-15.4) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Porphobilinogen (HMDB0000245) | 9.7 (21.8-10.5) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 5-Aminolevulinic acid (HMDB0001149) | 4.2 (9.9-6.7) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Porphobilinogen (HMDB0000245) | 2.3 (5.1-2.9) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 5-Aminolevulinic acid (HMDB0001149) | 1.5 (3.8-2.6) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details |
Short Chain Acyl-Coa Dehydrogenase Deficiency
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Ethylmalonic acid (HMDB0000622) | 182.0266-1152.0814 umol/mmol creatinine | Abnormal | Newborn (0-30 days old) | Female | details | |
| Glutaric acid (HMDB0000661) | 3.392-44.0934 umol/mmol creatinine | Abnormal | Newborn (0-30 days old) | Female | details | |
| Glutaric acid (HMDB0000661) | 4.522-9.0448 umol/mmol creatinine | Abnormal | Newborn (0-30 days old) | Female | details | |
| Methylsuccinic acid (HMDB0001844) | 22.612-101.754 umol/mmol creatinine | Abnormal | Newborn (0-30 days old) | Female | details | |
| Ethylmalonic acid (HMDB0000622) | 34.231-1012.319 umol/mmol creatinine | Abnormal | Newborn (0-30 days old) | Not Specified | details | |
| Isobutyrylglycine (HMDB0000730) | 0.0234-1.106 umol/mmol creatinine | Abnormal | Newborn (0-30 days old) | Not Specified | details |
Adenosine deaminase deficiency (102700 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| 1-Methyladenine (HMDB0011599) | 3.15 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Female | details | |
| Deoxyadenosine (HMDB0000101) | 176.0 (167.0-185.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Deoxyadenosine (HMDB0000101) | 10-190 umol/mmol creatinine | Abnormal | Infant (0-1 year old) | Not Specified | details | |
| Deoxyadenosine triphosphate (HMDB0001532) | 0-210000 umol/mmol creatinine | Abnormal | Infant (0-1 year old) | Not Specified | details |
Adenylosuccinate lyase deficiency (103050 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Succinyladenosine (HMDB0000912) | 101-188 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Adenosine (HMDB0000050) | 6.3-7.2 umol/mmol creatinine | Abnormal | Infant (0-1 year old) | Both | details | |
| Deoxyadenosine (HMDB0000101) | 2-7.2 umol/mmol creatinine | Abnormal | Infant (0-1 year old) | Both | details | |
| Succinyladenosine (HMDB0000912) | 96.6-281.9 umol/mmol creatinine | Abnormal | Infant (0-1 year old) | Both | details |
Adrenoleukodystrophy (300100 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Pipecolic acid (HMDB0000070) | 3.3 (1.5-5.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both |
| details |
| Pipecolic acid (HMDB0000070) | 49.4 (8.4-90.4) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both |
| details |
AIDS
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Butyric acid (HMDB0000039) | 0.18 +/- 0.044 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details |
Alcoholism
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Ethanol (HMDB0000108) | 3543.6 +/- 1414.6 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Male | details | |
| Methanol (HMDB0001875) | 15427.0 +/- 10168.0 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Male | details |
Alkaptonuria (203500 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Homogentisic acid (HMDB0000130) | 1819 (1134 - 2504) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Homogentisic acid (HMDB0000130) | > 2780 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details |
Alpha-aminoadipic aciduria
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Oxoadipic acid (HMDB0000225) | 20-120 umol/mmol creatinine | Abnormal | Children (1-13 years old) | Not Specified | details | |
| 2-Hydroxyadipic acid (HMDB0000321) | 80-170 umol/mmol creatinine | Abnormal | Children (1-13 years old) | Not Specified | details | |
| Aminoadipic acid (HMDB0000510) | 13000 umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both |
| details |
Pregnancy
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Estriol-3-glucuronide (HMDB0010335) | 0.95 +/- 0.45 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Estriol 3-sulfate 16-glucuronide (HMDB0010356) | 0.49 +/- 0.25 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Estriol-16-Glucuronide (HMDB0006766) | 1.58 +/- 0.86 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Female | details | |
| Estriol-3-glucuronide (HMDB0010335) | 0.43 +/- 0.86 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Female | details | |
| Monoethyl phthalate (HMDB0002120) | 0.009 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Sphinganine (HMDB0000269) | 0.00011 +/- 0.00015 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Female | details |
Aminoacylase I deficiency (609924 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Acetylglycine (HMDB0000532) | 170 +/- 18 nmol/mmol creatinine | Abnormal | Infant (0-1 year old) | Male | details | |
| N-Acetylserine (HMDB0002931) | 104 (99-111) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Not Specified | details |
Angina
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| 11-Dehydro-thromboxane B2 (HMDB0004242) | 0.0000733 +/- 0.0000266 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details |
Anorexia nervosa (606788 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Isovalerylglycine (HMDB0000678) | 7.7 +/- 4.8 umol/mmol creatinine | Abnormal | Adolescent (13-18 years old) | Female | details | |
| Suberic acid (HMDB0000893) | 9.5 +/- 3.9 umol/mmol creatinine | Abnormal | Adolescent (13-18 years old) | Female | details | |
| Ethylmalonic acid (HMDB0000622) | 7.1 +/- 4.4 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Female | details | |
| Adipic acid (HMDB0000448) | 8.6 +/- 8.3 umol/mmol creatinine | Abnormal | Adolescent (13-18 years old) | Female | details | |
| Glutaric acid (HMDB0000661) | 3.4 +/- 1.9 umol/mmol creatinine | Abnormal | Adolescent (13-18 years old) | Female | details | |
| Cortisol (HMDB0000063) | 0.44 +/- 0.09 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details |
Argininemia (207800 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Uracil (HMDB0000300) | 35.0 (20.0-50.0) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both |
| details |
| Uracil (HMDB0000300) | 144.265 umol/mmol creatinine | Abnormal | Children (1-13 years old) | Male | details |
Argininosuccinic aciduria (207900 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Argininosuccinic acid (HMDB0000052) | 667 umol/mmol creatinine | Abnormal | Infant (0-1 year old) | Male | details |
Asthma (600807 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| 1,7-Dimethyluric acid (HMDB0011103) | 20.0 (5.7-32.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 1,3-Dimethyluric acid (HMDB0001857) | 33.0 (21.8-52.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 7-Methylxanthine (HMDB0001991) | 10.0 (2.7-17.8) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 3-Methylxanthine (HMDB0001886) | 8.0 (5.0-14.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 1-Methylxanthine (HMDB0010738) | 6.0 (4.0-10.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Theobromine (HMDB0002825) | 3.6 (1.0-7.3) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Paraxanthine (HMDB0001860) | 3.6 (1.8-5.4) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Theophylline (HMDB0001889) | 7.0 (3.2-11.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 1,3,7-Trimethyluric acid (HMDB0002123) | 2.19 (0.0-5.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Caffeine (HMDB0001847) | 0.5 (0.0-1.35) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 11b-PGF2a (HMDB0010199) | 0.00021 (0.000099-0.00039) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details | |
| 11b-PGF2a (HMDB0010199) | 0.00044 (0.00016-0.00058) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details | |
| 3-Chlorotyrosine (HMDB0001885) | 0.0023 +/- 0.0016 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details |
Autism (209850 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| 3-(3-Hydroxyphenyl)-3-hydroxypropanoic acid (HMDB0002643) | 192.4 +/- 90.4 umol/mmol creatinine | Abnormal | Children (1-13 years old) | Male | details |
Autosomal dominant polycystic kidney disease (601313 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Asymmetric dimethylarginine (HMDB0001539) | 22.0 +/- 4.0 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 13S-hydroxyoctadecadienoic acid (HMDB0004667) | 467.0 +/- 67.0 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Symmetric dimethylarginine (HMDB0003334) | 22.0 +/- 8.0 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details |
Benzene exposure
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| trans-trans-Muconic acid (HMDB0002349) | 0.16 +/- 0.02 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Male | details |
Biliary atresia (210500 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Chenodeoxycholic acid glycine conjugate (HMDB0000637) | 0.032 +/- 0.058 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Glycolic acid (HMDB0000115) | 0.40 +/- 0.36 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Cholic acid (HMDB0000619) | 0.075 +/- 0.090 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Taurocholic acid (HMDB0000036) | 0.15 +/- 0.087 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Chenodeoxycholic acid (HMDB0000518) | 0.0092 +/- 0.013 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Taurochenodesoxycholic acid (HMDB0000951) | 0.013 +/- 0.021 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details |