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Browsing Urine Metabolite Diseases and Conditions
Clicking on any metabolite link will take you to the Human Metabolome Database.
2-Ketoglutarate dehydrogenase complex deficiency (203740 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Oxoglutaric acid (HMDB00208) | 101.0 (50.0-152.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Oxoglutaric acid (HMDB00208) | 875.0 (150.0-1600.0) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details |
3-Hydroxy-3-methylglutaryl-CoA lyase deficiency (246450 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| 3-Hydroxymethylglutaric acid (HMDB00355) | 5600.0 (200.0-11000.0) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details | |
| 3-Hydroxyisovaleric acid (HMDB00754) | 2030.0 (60.0-4000.0) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details | |
| 3-Methylcrotonylglycine (HMDB00459) | 225.0 (0.00-450.0) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details | |
| 3-Methylglutaconic acid (HMDB00522) | 5070.0 (140.0-10000.0) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details | |
| Methylglutaric acid (HMDB00752) | 507.0 (14.0-1000.0) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details | |
| Adipic acid (HMDB00448) | 31.0 (12.0-50.0) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details | |
| 3-Hydroxyisovaleric acid (HMDB00754) | 23.0 (0.0-46.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Methylglutaric acid (HMDB00752) | 3.5 (0.0-7.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 3-Methylglutaconic acid (HMDB00522) | 4.5 (0.00-9.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Adipic acid (HMDB00448) | 17.15 (0.00-34.30) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details |
3-Methylglutaconic aciduria type I (250950 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| 3-Hydroxyisovaleric acid (HMDB00754) | 200.0 (150.0-250.0) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details | |
| Methylglutaric acid (HMDB00752) | 7.5 (5.0-10.0) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details | |
| 3-Methylglutaconic acid (HMDB00522) | 750.0 (500.0-1000.0) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details |
Succinic semialdehyde dehydrogenase deficiency (271980 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| (S)-3,4-Dihydroxybutyric acid (HMDB00337) | 137.5 (50.0-225.0) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details | |
| (S)-3,4-Dihydroxybutyric acid (HMDB00337) | 98.0 (30.0-166.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details |
Appendicitis
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Indoleacetic acid (HMDB00197) | 3.5 +/- 0.33 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Indoleacetic acid (HMDB00197) | 3.1 +/- 0.14 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details |
Medium Chain Acyl-CoA Dehydrogenase Deficiency (201450 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| 5-Hydroxyhexanoic acid (HMDB00525) | 357.5 (15.00-700.00) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details | |
| 7-Hydroxyoctanoic acid (HMDB00486) | 152.00 (4.00-300.00) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details | |
| Hexanoylglycine (HMDB00701) | 366.0 (2.00-730.00) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details | |
| 2-Octenedioic acid (HMDB00341) | 125.00 (0.00-250.00) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details | |
| Phenylpropionylglycine (HMDB00860) | 45.5 (1.00-90.00) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details | |
| Suberylglycine (HMDB00953) | 1100.00 (6.00-2200.00) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details | |
| Suberylglycine (HMDB00953) | 1.00 (0.00-2.00) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Phenylpropionylglycine (HMDB00860) | 1.00 (0.00-2.00) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| cis-4-Decenedioic acid (HMDB00603) | 1.00 (0.00-2.00) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 5-Hydroxyhexanoic acid (HMDB00525) | 3.5 (0.0-7.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 7-Hydroxyoctanoic acid (HMDB00486) | 1.00 (0.00-2.00) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 2-Octenedioic acid (HMDB00341) | 7.00 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details |
Short Chain Acyl-Coa Dehydrogenase Deficiency
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| N-Butyrylglycine (HMDB00808) | 2.0 (0.38-3.8) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details | |
| Methylsuccinic acid (HMDB01844) | 40.00 (20.00-60.00) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details | |
| Hexanoylglycine (HMDB00701) | 1.6 (0.00-3.26) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details |
Adenosine deaminase deficiency (102700 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Deoxyadenosine (HMDB00101) | 0.005 (0.000-0.010) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 1-Methyladenine (HMDB11599) | 3.15 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Female | details | |
| Deoxyadenosine (HMDB00101) | 176.0 (167.0-185.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details |
Adenylosuccinate lyase deficiency (103050 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| SAICAR (HMDB00797) | 214 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Succinyladenosine (HMDB00912) | 101-188 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details |
Adrenoleukodystrophy (300100 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Pipecolic acid (HMDB00070) | 3.3 (1.5-5.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Pipecolic acid (HMDB00070) | 49.4 (8.4-90.4) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details |
Refsum's disease (266500 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Methylsuccinic acid (HMDB01844) | 1.9 (1.3-2.5) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 3-Methyladipic acid (HMDB00555) | 5.9 (3.0-8.5) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Pipecolic acid (HMDB00070) | 2.0 umol/mmol creatinine | Abnormal | Infant (0-1 year old) | Both | details |
AIDS
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Butyric acid (HMDB00039) | 0.18 +/- 0.044 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details |
Alcoholism
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Ethanol (HMDB00108) | 3543.6 +/- 1414.6 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Male | details | |
| Methanol (HMDB01875) | 15427.0 +/- 10168.0 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Male | details |
Alkaptonuria (203500 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Homogentisic acid (HMDB00130) | 1819 (1134 - 2504) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Homogentisic acid (HMDB00130) | > 2780 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Homogentisic acid (HMDB00130) | 1.0 (0.0-2.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Homogentisic acid (HMDB00130) | 3000.0 (1000.0-5000.0) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details |
Alzheimer's disease (104300 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| L-Histidine (HMDB00177) | 30.5 +/- 4.3 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Glycylproline (HMDB00721) | 0.0087 +/- 0.0016 umol/mmol creatinine | Abnormal | Elderly (>65 years old) | Both | details | |
| L-Arginine (HMDB00517) | 2.0 +/- 0.21 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 1-Methylhistidine (HMDB00001) | 15.7 +/- 4.04 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 3-Methylhistidine (HMDB00479) | 24.0 +/- 1.7 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Carnosine (HMDB00033) | 18.8 +/- 10.31 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| L-Tryptophan (HMDB00929) | 1.19 +/- 0.23 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Citrulline (HMDB00904) | 21.0 +/- 2.8 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Ornithine (HMDB00214) | 12.34 +/- 5.07 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| L-2,4-diaminobutyric acid (HMDB06284) | 36.0 +/- 5.0 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| L-Glutamine (HMDB00641) | 1.17 +/- 0.49 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 4-Hydroxy-L-proline (HMDB06055) | 0.21 +/- 0.017 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| L-Isoleucine (HMDB00172) | 0.13 +/- 0.04 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| L-Lysine (HMDB00182) | 5.5 +/- 1.74 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| L-Cystine (HMDB00192) | 72.03 +/- 12.0 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| L-Cystathionine (HMDB00099) | 1.68 +/- 0.5 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Glycine (HMDB00123) | 0.010 +/- 0.001 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| L-Valine (HMDB00883) | 0.73 +/- 0.12 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| L-Leucine (HMDB00687) | 0.91 +/- 0.11 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Anserine (HMDB00194) | 8.0 +/- 5.0 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| L-Phenylalanine (HMDB00159) | 1.37 +/- 0.18 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| L-Tyrosine (HMDB00158) | 10.5 +/- 1.5 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| L-Threonine (HMDB00167) | 0.03 +/- 0.003 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details |
Pregnancy
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Estriol-3-glucuronide (HMDB10335) | 0.95 +/- 0.45 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Estriol 3-sulfate 16-glucuronide (HMDB10356) | 0.49 +/- 0.25 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Estriol-16-Glucuronide (HMDB06766) | 1.58 +/- 0.86 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Female | details | |
| Estriol-3-glucuronide (HMDB10335) | 0.43 +/- 0.86 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Female | details | |
| Monoethyl phthalate (HMDB02120) | 0.009 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Sphinganine (HMDB00269) | 0.00011 +/- 0.00015 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Female | details |
Aminoacylase I deficiency (609924 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Acetylglycine (HMDB00532) | 170 +/- 18 nmol/mmol creatinine | Abnormal | Infant (0-1 year old) | Male | details | |
| N-Acetylserine (HMDB02931) | 104 (99-111) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Not Specified | details |
Angina
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| 11-Dehydro-thromboxane B2 (HMDB04242) | 0.0000733 +/- 0.0000266 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details |
Anorexia nervosa (606788 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Isovalerylglycine (HMDB00678) | 7.7 +/- 4.8 umol/mmol creatinine | Abnormal | Adolescent (13-18 years old) | Female | details | |
| Suberic acid (HMDB00893) | 9.5 +/- 3.9 umol/mmol creatinine | Abnormal | Adolescent (13-18 years old) | Female | details | |
| Ethylmalonic acid (HMDB00622) | 7.1 +/- 4.4 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Female | details | |
| Adipic acid (HMDB00448) | 8.6 +/- 8.3 umol/mmol creatinine | Abnormal | Adolescent (13-18 years old) | Female | details | |
| Glutaric acid (HMDB00661) | 3.4 +/- 1.9 umol/mmol creatinine | Abnormal | Adolescent (13-18 years old) | Female | details | |
| Cortisol (HMDB00063) | 0.44 +/- 0.09 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details |
Argininemia (207800 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| Argininosuccinic acid (HMDB00052) | 0.65 (0.0-1.3) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details | |
| Uracil (HMDB00300) | 35.0 (20.0-50.0) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details | |
| Uracil (HMDB00300) | 12.0 (2.0-22.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details |
Aromatic L-amino acid decarboxylase deficiency (107930 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| N-Acetylvanilalanine (HMDB11716) | 10 +/- 2 umol/mmol creatinine | Abnormal | Infant (0-1 year old) | Male | details | |
| Vanilpyruvic acid (HMDB11714) | 10 +/- 2 umol/mmol creatinine | Abnormal | Infant (0-1 year old) | Male | details | |
| N-Acetyl-L-tyrosine (HMDB00866) | 10 +/- 2 umol/mmol creatinine | Abnormal | Infant (0-1 year old) | Male | details | |
| Vanillylmandelic acid (HMDB00291) | 0.15 (0.00-0.30) umol/mmol creatinine | Abnormal | Infant (0-1 year old) | Male | details | |
| 5-Hydroxyindoleacetic acid (HMDB00763) | 0.9 +/- 0.0 umol/mmol creatinine | Abnormal | Infant (0-1 year old) | Male | details | |
| Homovanillic acid (HMDB00118) | 2.9 +/- 0.0 umol/mmol creatinine | Abnormal | Infant (0-1 year old) | Male | details | |
| Dopamine (HMDB00073) | 2426 +/- 0 nmol/mmol creatinine | Abnormal | Infant (0-1 year old) | Male | details | |
| Dopamine (HMDB00073) | 3.119 +/- 0 umol/mmol creatinine | Abnormal | Infant (0-1 year old) | Male | details |
Asthma (600807 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| 1,7-Dimethyluric acid (HMDB11103) | 20.0 (5.7-32.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 1,3-Dimethyluric acid (HMDB01857) | 33.0 (21.8-52.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 7-Methylxanthine (HMDB01991) | 10.0 (2.7-17.8) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 3-Methylxanthine (HMDB01886) | 8.0 (5.0-14.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 1-Methylxanthine (HMDB10738) | 6.0 (4.0-10.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Theobromine (HMDB02825) | 3.6 (1.0-7.3) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Paraxanthine (HMDB01860) | 3.6 (1.8-5.4) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Theophylline (HMDB01889) | 7.0 (3.2-11.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 1,3,7-Trimethyluric acid (HMDB02123) | 2.19 (0.0-5.0) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| Caffeine (HMDB01847) | 0.5 (0.0-1.35) umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details | |
| 11b-PGF2a (HMDB10199) | 0.00021 (0.000099-0.00039) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details | |
| 11b-PGF2a (HMDB10199) | 0.00044 (0.00016-0.00058) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details | |
| 3-Chlorotyrosine (HMDB01885) | 0.0023 +/- 0.0016 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Both | details |
Autism (209850 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| 3-(3-Hydroxyphenyl)-3-hydroxypropanoic acid (HMDB02643) | 192.4 +/- 90.4 umol/mmol creatinine | Abnormal | Children (1-13 years old) | Male | details |
Benzene exposure
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| trans-trans-Muconic acid (HMDB02349) | 0.16 +/- 0.02 umol/mmol creatinine | Abnormal | Adult (>18 years old) | Male | details |
3-methyl-crotonyl-glycinuria (210200 )
| Metabolite | Concentration in Urine | Patient Status | Age | Sex | Reference | Details |
|---|---|---|---|---|---|---|
| 3-Hydroxyisovaleric acid (HMDB00754) | 30350.0 (1700-59000.0) umol/mmol creatinine | Abnormal | Children (1-13 years old) | Both | details |